Home > Academic Announcements > (Nov. 9) Frontiers in Medical Sciences Lecture 310-Mutations in ACTL6B cause a dominant intellectual disability syndrome and profound loss of dendrites in human neurons

(Nov. 9) Frontiers in Medical Sciences Lecture 310-Mutations in ACTL6B cause a dominant intellectual disability syndrome and profound loss of dendrites in human neurons

Last updated :2017-11-01

Topic: Mutations in ACTL6B cause a dominant intellectual disability syndrome and profound loss of dendrites in human neurons
Speaker: Dr. Carl Ernst
(Associate Professor & Researcher, McGill University, Canada)
Host: Professor Peng Xiang (Zhongshan School of Medicine, SYSU)
Time: 11:00-12:00 am, Thursday, November 9, 2017
Venue: Lecture Hall, 4th Floor, Yongsheng Building, Guangzhou North Campus, SYSU

About the speaker:
Prof. Carl Ernst studies neurodevelopmental disorders using Next-Generation sequencing technology, gene editing, and stem cell biology. In this talk, he will be presenting their latest progress on creating iPS cells from patients with neurodevelopmental disorders, their optimized strategy for efficient correction of genetic mutation(s) in patient-derived iPS cells with CRISPR/Cas9 method. He will do this using a case study of a new disorder they have discovered. Finally, he will also discuss the current status and future prospects of iPS derived neuronal models for mechanistic understanding of brain diseases.