Research News
-
Prof. Bin Wu's team revealed a key mechanism of aerobic glycolysis in the process of hepatitis B virus-related HCC
Aerobic glycolysis is considered a hallmark feature of cancer. Recently, Prof. Bin Wu's team from the Third Affiliated Hospital of Sun Yat-sen University published an original article entitled "Aerobic glycolysis enhances HBx-initiated hepatocellular carcinoma via NF-κBp65/HK2 signaling" online in the Journal of Experimental & Clinical Cancer Research on Nov. 21th, revealed a key mechanism of ...
December 6, 2022
-
The research team of Prof. Shicheng Su revealed a new mechanism of the pro-tumor effect mediated by Fcγ receptor signals in non-leukocyte cells
Recently, the research team directed by Prof. Shicheng Su from Sun Yat-sen Memorial Hospital, Sun Yat-sen University, revealed a new mechanism of the pro-tumor effect mediated by Fcγ receptor signals in non-leukocyte cells. This work entitled "CD16+ Fibroblasts Foster a Trastuzumab-Refractory Microenvironment That is Reversed by VAV2 Inhibition" was published online in Cancer Cell on Nov. 14th.
November 24, 2022
-
Prof. Kuang Ming's team and Prof. Lin Shuibin's team co-published an article on intrahepatic cholangiocarcinoma immunotherapy
Recently, Prof. Kuang Ming's team (Center for Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University) and Prof. Lin Shuibin's team (Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University) co-published a research article entitled “Targeting tumor-intrinsic N7-methylguanosine tRNA modification inhibits MDSC recruitment and improves...
November 8, 2022
-
Professor Ming Kuang's group revealed the epigenetic mechanism of lenvatinib resistance in HCC
Recently, Prof. Ming Kuang's research team from the First Affiliated Hospital, Sun Yat-sen University published a research paper entitled “METTL1-mediated m7G tRNA modification promotes lenvatinib resistance in hepatocellular carcinoma” online in Cancer Research, which deciphered novel mechanisms underlying lenvatinib resistance from a translation level perspective.
October 21, 2022
-
Novel Finding of FOXP3+ Macrophage Which Represses Acute Ischemic Stroke-induced Neural Inflammation by Zhengqi Lu's Group
Recently, Professor Zhengqi Lu's group from the Department of Neurology, Mental and Neurological Disease Research Center, the Third Affiliated Hospital of Sun Yat-sen University, published the latest original research entitled “FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation”in Autophagy. The study found that FOXP3+ macrophages suppressed acute ischemic stroke-in...
October 12, 2022