Radiation-induced brain injury (RIBI) is a debilitating sequela after radiotherapy to treat head and neck cancer, with clinical manifestations including cognitive impairment and pathological changes such as brain tissue edema and necrosis. Although corticosteroids and bevacizumab can be used as first-line treatment at present, there are still a majority of RIBI patients fail to respond to or ha...
Recently, Prof. Qiyi Zhao's group from the Third Affiliated Hospital of Sun Yat-sen University, published the latest original research entitled “Niche stiffness sustains cancer stemness via TAZ and NANOG phase separation” in Nature Communications.Emerging evidence shows that the biomechanical environment is required to support cancer stem cells (CSCs), which play a crucial role in drug resist...
Infancy and early childhood are critical periods for visual development, during which imprompt detection and treatment for ocular disorders can result in irreversible visual loss and bring a heavy burden to the family and society. The incidence of eye diseases is reported approximately 9.11% among the 50 million young children under 4 years old in China. Early detection and prompt treatment are...
On January 3rd, 2023, the research finding “Distinct Single-cell Immune Ecosystems Distinguish True and De Novo HBV-related Hepatocellular Carcinoma Recurrences” was published online in Gut (IF=31.79), the Journal of the British Society of Gastroenterology and the top journal in the field of gastroenterology, by Professor Ming Kuang's team from the Center of Hepato-Pancreato-Biliary Surgery, ...
Radiation-induced brain injury (RIBI) remains as the most serious medical complication in head and neck cancer patients who received cranial radiotherapy. The clinical manifestations of RIBI include cognitive impairment, epilepsy, and pathological changes such as brain edema and tissue necrosis, which can occur within 3-5 years after the radiotherapy. The progressive development of brain lesion...
Anthropogenic climate change is now influencing the population dynamics of many species. Its impact is often mediated by effects on the local environmental conditions that determine key biological processes such as fecundity and mortality. For animals living in seasonal environments in temperate regions, individuals usually suffer most mortality over winter, and winter mortality may therefore c...
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