Radiation-induced brain injury (RIBI) remains as the most serious medical complication in head and neck cancer patients who received cranial radiotherapy. The clinical manifestations of RIBI include cognitive impairment, epilepsy, and pathological changes such as brain edema and tissue necrosis, which can occur within 3-5 years after the radiotherapy. The progressive development of brain lesion...
Anthropogenic climate change is now influencing the population dynamics of many species. Its impact is often mediated by effects on the local environmental conditions that determine key biological processes such as fecundity and mortality. For animals living in seasonal environments in temperate regions, individuals usually suffer most mortality over winter, and winter mortality may therefore c...
The rediscovery of N6-deoxyadenosine (6mA) in eukaryotic genomes has sparked interest in its potential as a new epigenetic marker. In recent years, 6mA has been identified in various eukaryotes, including plants, vertebrates, and mammals. However, limitations in current methods, particularly the inability to accurately identify the location of 6mA, have hindered further research into its mechan...
At present, the frequency of flood disasters has increased sharply around the world, and the scope of disasters has expanded year by year, and it has become one of the most important agricultural disasters. Prolonged plant immersion in flood/flooded environments can lead to a significant decrease in rhizosphere oxygen content, resulting in hypoxic stress (hypoxia); Long-term flooding stress wil...
Some observational studies had found that shift work would increase risks of metabolic disorders, cancers, and cardiovascular diseases by affecting sleep time, circadian rhythm, and other mechanisms, but there was no homogeneous evidence of such an association between shift work and incident dementia, which has important public health implications for the physical and mental health of shift wor...
A large number of small open reading frames (sORFs) are predicted to exist in the transcripts previously annotated as non-coding RNAs or untranslated regions of protein-coding genes. Emerging evidence show that sORFs may encode micropeptides with less than 100 amino acids. To date, only a small fraction of the putative micropeptides has been functionally characterized. More extensive investigat...
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