State Key Laboratory Approved by: Ministry of Science and Technology
| No. | Name of Institute | Unit at SYSU | Year of Establishment |
| 1 | State Key Laboratory of Optoelectronic Materials and Technologies (Sun Yat-sen University) | School of Electronics and Information Technology/ School of Physics/ School of Materials Science and Engineering/ School of Chemistry | 1984 |
| 2 | State Key Laboratory of Biocontrol (Sun Yat-sen University) | School of Life Sciences | 1991 |
| 3 | State Key Laboratory of Oncology in South China (Sun Yat-sen University) | Cancer Center | 2005 |
| 4 | State Key Laboratory of Ophthalmology (Sun Yat-sen University) | Zhongshan Ophthalmic Center | 2006 |
National Engineering Research Center Approved by: National Development and Reform Commission
| No. | Name of Institute | Unit at SYSU | Year of Establishment |
| 1 | National Engineering Research Center of South China Sea Marine Biotechnology | School of Marine Sciences | 2002 |
National Engineering Technology Research Center Approved by: Ministry of Science and Technology
| No. | Name of Institute | Unit at SYSU | Year of Establishment |
| 1 | National Engineering Research Center of Digital Life | School of Data and Computer Science | 2010 |
Clinical Trial Research Center Approved by: Ministry of Science and Technology
| No. | Name of Institute | Unit at SYSU | Year of Establishment |
| 1 | National Clinical Study Center for Anticancer Drugs | Cancer Center | 2001 |
National Center for International Joint Research Approved by: Ministry of Science and Technology
| No. | Name of Institute | Unit at SYSU | Year of Establishment |
| 1 | International Joint Research Center for Translational Medicine | Zhongshan School of Medicine | 2013 |
International Science and Technology Cooperation Base Approved by: Ministry of Science and Technology
| No. | Name of Institute | Unit at SYSU | Year of Establishment |
| 1 | International Science and Technology Cooperation Base of IncRNA and Serious Diseases | Sun Yat-sen Memorial Hospital | 2016 |
State-Province Joint Engineering Laboratory Approved by: National Development and Reform Commission
| No. | Name of Institute | Unit at SYSU | Year of Establishment |
| 1 | State-Province Joint Engineering Laboratory of Molecular Diagnosis of Clinical Medicine | DAAN Gene Co., Ltd. | 2011 |
| 2 | State-Province Joint Engineering Laboratory of Digital Home Interactive Applications | School of Data and Computer Science | 2011 |
| 3 | State-Province Joint Engineering Laboratory of Semiconductor Lighting Materials and Devices | School of Electronics and Information Technology | 2011 |
| 4 | State-Province Joint Engineering Laboratory of Estuarine Hydraulic Technology | School of Marine Sciences / School of Marine Engineering and Technology | 2011 |
| 5 | State-Province Joint Engineering Laboratory of IOT IC and System Application Technologies | School of Electronics and Information Technology | 2012 |
| 6 | State-Province Joint Engineering Laboratory of Druggability and New Drugs Evaluation | School of Pharmaceutical Sciences | 2013 |
| 7 | State-Province Joint Engineering Laboratory of Diagnosis and Treatment of Vascular Diseases | The First Affiliated Hospital | 2015 |
State-Province Joint Engineering Research Center Approved by: National Development and Reform Commission
| No. | Name of Institute | Unit at SYSU | Year of Establishment |
| 1 | State-Province Joint Engineering Research Center of RFID and IoT Tag Technologies | School of Electronics and Information Technology | 2015 |
| 2 | State-Province Joint Engineering Research Center of Stem Cells and Regenerative Medicine | Zhongshan School of Medicine | 2018 |
National Engineering Laboratory Approved by: National Development and Reform Commission
| No. | Name of Institute | Unit at SYSU | Year of Establishment |
| 1 | National Engineering Laboratory for AMOLED Process Technology | School of Electronics and Information Technology | 2016 |
Collaborative Innovation Center Approved by: Ministry of Education
| No. | Name of Institute | Unit at SYSU | Year of Establishment |
| 1 | Collaborative Innovation Center for Cancer Medicine | Cancer Center | 2018 |
Key Research Institute of Humanities and Social Sciences at Universities Approved by: Ministry of Education
| No. | Name of Institute | Unit at SYSU | Year of Establishment |
| 1 | Institute of Logic and Cognition, Sun Yat-sen University | Department of Philosophy | 2000 |
| 2 | Center for Studies of Hong Kong, Macao and Pearl River Delta, Sun Yat-sen University |
| 2000 |
| 3 | Institute of Marxist Philosophy and Chinese Modernization | Department of Philosophy | 2000 |
| 4 | Center for Chinese Public Administration Research | School of Government | 2001 |
| 5 | Centre for Historical Anthropology, Sun Yat-sen University | Department of History | 2004 |
| 6 | Institute of Chinese Intangible Cultural Heritage, Sun Yat-sen University | Department of Chinese | 2004 |
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